The earlier findings that under hypoxic conditions expression of BNIP3 can be induced by the transcription factor HIF-1α (Bruick, 2000; Guo et al, 2001; Sowter et al, 2001) prompted us to evaluate the extent to which expression of BNIP3 in haematopoietic tumour cell lines could be induced by hypoxia. This evidence concerns the gene BNIP3 and neoplasm.