CD200 and a viral homologue found in Kaposi sarcoma virus, when expressed at the cell surface, gave inhibition of production of inflammatory cytokines from activated macrophages [24]; and targeting the CD200-CD200R interaction with agonistic mAb or CD200-Fc fusion proteins in vivo ameliorates autoimmunity in disease models [25,26]. Here, CD200 is linked to Autoimmunity.