Measurement of mRNA levels of the CXCR3 ligands demonstrated that unstimulated alveolar macrophages isolated from the BAL of HP subjects expressed increased mRNA levels of CXCL9 and CXCL10 with respect to macrophages obtained from control subjects (Table 2 and figure 7). The gene discussed is CXCR3; the disease is hypersensitivity pneumonitis.