The surface ratio (S-S0) / S0 of migration was reduced by inhibition of the gap junction function (5.59 ± 0.49 for CBX-treated vs. 7.82 ± 0.70 in untreated controls; p < 0.01) (Fig. 2C), as well as the number of GL15 cells that left the tumor mass (105 ± 6.3 cells/mm of perimeter vs. 132 ± 7.2; p < 0.01) (Fig. 2D). Here, CBX1 is linked to neoplasm.