AZGP1 and Cachexia: A potential mediator of this increased lipolysis is a lipid-mobilising factor (LMF), which has been isolated both from a cachexia-inducing murine adenocarcinoma (MAC16), and from the urine of patients with cancer cachexia, and has been shown to be identical with the plasma protein zinc-α2-glycoprotein (ZAG) (Todorov et al, 1998).