CD4 and head and neck squamous cell carcinoma: However, even this rapid replacement does not seem to correct absolute CD4+ T lymphocyte count in patients with SCCHN, which ranged from 120 to 1227 mm−3, with a mean of 610±350 (s.d.)mm−3 in our patient cohort, and was significantly lower from the normal mean of 1005±360 mm−3 (P<0.001).