DCK and pancreatic neoplasm: An increase in dCK expression was also observed after gemcitabine exposure in pancreatic cancer PANC-1 and Capan-1 cells (Giovannetti et al, 2004), suggesting that treatment with inhibitors of DNA synthesis could potentiate the dCK expression of various cells, because the salvage pathway initiated by dCK accounts for the majority of nucleotide synthesis for DNA repair.