ERBB2 and neoplasm: Additionally, in the same group an age at first full pregnancy >23 years revealed an increase of risk in both HER-2/neu groups, while first degree family history (OR = 2.72, 95%C.I: 1.05–7.07, p = 0.040), age at menopause >50 years (OR = 2.05, 95%C.I: 1.10–3.79, p = 0.023) and birth of 1–2 children (OR = 2.38, 95%C.I: 1.21–4.67, p = 0.012) elevated risk for HER-2/neu negative tumours only.