Since this action appears to result from an effect on regulation of cell cycle progression and induction of apoptosis (Ahmad et al, 1997, 2000, 2002; Gupta et al, 2000) rather than from an unspecific antioxidant function (Salucci et al, 2002), tNOX protein has been proposed as the molecular target on cancer cells to explain their specific inhibition of growth by EGCg (Morré et al, 2000). Here, ENOX2 is linked to cancer.