ERCC2 and colorectal cancer: In 2003, Mort et al. [22] noted that the risk of suffering colorectal cancer was significantly heightened for individuals who featured the XRCC3 241Thr allele (OR = 1.52, 95% CI = 1.04–2.22) and only slightly increased for those individuals who revealed the XRCC1 399Gln and XPD 751Gln alleles.