VEGFA and neoplasm: The resulting multivariate analysis revealed that DFS and OS were improved in patients with low total VEGF (P<0.001 and P=0.043), a high S/V ratio (P=0.002 and 0.003), pathological low grade (P=0.015 and 0.034), tumour less than 5 cm in size (P=0.002 and 0.038) and negative nodal involvement (P=0.001 and 0.002, respectively) (Table 5).