Sonnenberg et al. [8] have hypothesized that increased adipose tissue mass contributes to the development of MetS by triggering an increase in proinflammatory adipokines, especially the tumor necrosis factor-α, which may play a role in the pathogenesis of dyslipidemia, insulin resistance, hypertension, endothelial dysfunction, and atherogenesis. Here, TNF is linked to metabolic syndrome.