Overexpression of multiple FGFs (namely aFGF/FGFl, bFGF/FGF2, FGF6 and FGF8) has been identified in prostate cancer (Leung et al, 1996; Ittmann and Mansukhani, 1997; Dorkin et al, 1999b; Ropiquet et al, 2000). Here, FGF2 is linked to Familial prostate cancer.