EGFR and breast carcinoma: Epidermal growth factor receptor-associated protein tyrosine kinase complexes also have vital antiapoptotic functions in human breast cancers (Modjtahedi et al, 1998; Witters et al, 1999) and the blockade of EGFR not only adversely affected cell growth, but also showed a sign of terminal differentiation and induces apoptosis in the human cancer cells (Modjtahedi et al, 1998).