MUC5AC and colorectal adenocarcinoma: Most evidence suggests that colorectal adenocarcinomas that produce an abundance of the glycoprotein mucin portend a worse clinical prognosis (Umpleby et al, 1985; Green et al, 1993; Nozoe et al, 2000), although this finding has not been consistently established (Sasaki et al, 1987; Halvorsen and Seim, 1988).