BIRC5 and urinary bladder neoplasm: Our data seem to go against the original hypothesis that survivin might predict a more aggressive clinical outcome, although some evidences have been reported documenting the absence of any association between survivin expression and prognosis in some solid tumours (Grabowski et al, 2003; Li, 2003), and even a favourable prognostic role of high nuclear survivin content in gastric and bladder tumours (Okada et al, 2001; Lehner et al, 2002).