BIRC5 and ovarian carcinoma: However, it has to be taken into account that this is the first study examining the clinical relevance of survivin status in terms of clinical outcome in a single-institution large series of ovarian carcinomas, compared to previous reports which referred to very small sample series (Yoshida et al, 2001; Sui et al, 2002; Takai et al, 2002), sometimes biased by the inclusion of selected groups of patients (Yoshida et al, 2001).