APOE and Alzheimer disease: After adjustment for age, sex, educational level, and ethnicity, the odds ratio (OR) of NSAID use among AD cases compared to non-users was 0.57 (95% CI = 0.35–0.93); it was 0.64 (95% CI = 0.38–1.05) when APOE carrier status was added to the GEE model (see Table 2).