MKI67 and invasive breast carcinoma: Papantoniou and colleagues [25] recently reported this factor to be independently correlated with focal 99mTc-(V)DMSA accumulation in invasive breast cancer, while their preliminary reports [26] revealed that cases of usual type hyperplasia imaged with 99mTc-(V)DMSA tend to be related to elevated Ki-67 values and are therefore at risk of developing breast malignancy, according to the literature [27-31].