AGT and hypertensive disorder: However, no difference was observed in the AGT allele frequency distribution with respect to age and gender (Table 3, P > 0.05), and the effect of the AGT T allele did not reach a significant level in the decrease of hypertension risk (odds ratio: T vs. M: 0.88; 95% CI: 0.75 to 1.03; P = .12).