Adrenomedullin, the ligand for the CRLR/RAMP3 receptor dimer, functions as a growth factor in several human tumour cell lines [52], in addition to promoting angiogenesis in vivo [53] via CRLR/RAMP3 and CRLR/RAMP2 receptor dimers [54,55]. Here, RAMP3 is linked to neoplasm.