Extrapolating from these various results one may assume that where avoidance of c-Myc induced apoptosis is a product of cellular immaturity (as may be the case in some stem cell populations), then as long as c-Myc inactivation induces differentiation, and, presumably, no anti-apoptotic mutation has been acquired, a transient period may suffice for sustained tumour regression. Here, MYC is linked to neoplasm.