In ovarian carcinomas, the reported frequency of KIT and PDGFRA expression has been highly variable, and little is known about their molecular background and association with clinical parameters (Henriksen et al, 1993; Inoue et al, 1994; Arber et al, 1998; Dabrow et al, 1998; Parrott et al, 2000; Tonary et al, 2000; Schmandt et al, 2003; Singer et al, 2003; Apte et al, 2004a; Matei et al, 2004). The gene discussed is KIT; the disease is ovarian carcinoma.