CXCL8 and cancer: CXCL8 has been shown to be mitogenic for cancers such as melanoma (Schadendorf et al, 1993), colon cancer (Brew et al, 2000; Li et al, 2001), pancreatic cancer (Miyamoto et al, 1998), malignant mesothelioma (Galffy et al, 1999) and Kaposi's sarcoma (Masood et al, 2001).