To investigate this possibility we extracted RNA from pre-B cell lines as well as neuroblastoma cells and investigated the expression of the pre-B cell EBF target genes CD19 [19] and mb-1 [13] as well as the potential neuroblastoma EBF target genes SCG10 and CGA [5] by RT-PCR (Figure 2). The gene discussed is STMN2; the disease is neuroblastoma.