Elevated expression levels of Pax-5 has been detected in two other tumors of neuronal origin, medulloblastoma [35] and astrocytoma [36] and in vitro data [37] as well as observed translocations in human B lineage tumors [38-40] indicate that Pax-5 have oncogenic properties. Here, PAX5 is linked to astrocytoma (excluding glioblastoma).