Bearing in mind this observation, the fact that four of five of the informative tumours showed strong biallelic S100A2 expression and considering that the products of TP73L were scored as significantly tumour over-represented in 24% (nine out of 37) of samples in our microarray analysis, we examined the expression of this gene in this independent NSCLC series. The gene discussed is S100A2; the disease is neoplasm.