Finally, by comparative multiplex RT–PCR (cmRT–PCR), we have examined the expression of ΔNp63 in the tissue samples following the recent suggestion that S100A2 is a target of the ΔNp63 oncogenic pathway (Hibi et al, 2003) and bearing in mind that the p63 transcript was also highlighted in our microarray-generated, tumour over-represented gene lists (>two-fold in 24%, nine out of 37 patients). Here, TP63 is linked to neoplasm.