In this report, we investigated the ability of both peripheral blood lymphocytes (PBL) and TIL of undifferentiated NPC patients to express three interleukins (IL-2, IL-6, IL-10) and three immunoglobulin isotypes (IgM, IgG, IgA) following pokeweed mitogen (PWM) stimulation in vitro. This evidence concerns the gene IL10 and nasopharyngeal carcinoma.