Deregulated or aberrant expression of c-myc, via mechanisms including translocation, proviral insertion, locus amplification, point mutation, direct transcriptional and translational effects, or post-translational modifications, is a signature of several different human tumour types and c-myc can induce tumorigenesis under conditions where programmed cell death is abrogated (Evan et al, 1992; Santoni-Rugiu et al, 1998; Dang, 1999). This evidence concerns the gene MYC and neoplasm.