LMNA and Emery-Dreifuss muscular dystrophy: Emery-Dreifuss muscular dystrophy (EDMD) is inherited through mutations in either of two different genes: LMNA, encoding A-type lamins, and STA, which encodes a nuclear membrane protein named emerin (Nagano et al. 1996; Emery 2000; Bengtsson and Wilson 2004).