The highest mean microvessel density (MVD) and the highest VEGF/KDR (vascular endothelial growth factor bound to its receptor on endothelial cells)-activated microvessel density (aMVD) have been shown to be at the invading front of the tumours in NSCLC (Giatromanolaki et al, 2000; Koukourakis et al, 2000). Here, KDR is linked to neoplasm.