B-cell lymphomas from transgenic Eμ-myc mice also show a dependence on p19Arf to activate p53, and Eμ-myc mice lacking either p19Arf or p53 developed lymphomas much faster (Eischen et al. 1999; Schmitt et al. 1999). Here, TP53 is linked to B-cell non-Hodgkin lymphoma.