For example, CAV1 expression is increased in prostate cancer (Yang et al, 1999), oesophageal cancer (Kato et al, 2002) and ovarian cancer (Davidson et al, 2001), but reduced in colon cancer (Bender et al, 2000), lung cancer (Ho et al, 2002) and sarcoma (Wiechen et al, 2001). This evidence concerns the gene CAV1 and prostate carcinoma.