CDKN2A and neuroblastoma: Although alterations of the CDKN2A gene have been reported in many malignancies, it is a rare event in neuroblastoma (NB) (Beltinger et al, 1995; Kawamata et al, 1996; Castresana et al, 1997; Takita et al, 1997; Iolascon et al, 1998).