KLK6 and exocrine pancreatic carcinoma: As chromosome 19q13 is nonrandomly rearranged in many human solid tumours including pancreatic carcinomas, astrocytomas, thyroid tumours, and ovarian cancers (Mitelman, 1994, pp 3067–3198), gene amplification is likely another mechanism for the elevated expression of hK6 in ovarian tumours.