CYP1B1 and neoplasm: In contrast, to other cytochrome P450 enzymes, CYP1B1 is not expressed in human liver (Murray et al, 1997; Edwards et al, 1998), but demonstrates enhanced expression of immunoreactive protein in a wide range of histologically diverse tumours including kidney, ovarian, breast and colon tumours (Murray et al, 1997; McFadyen et al, 1999, 2001a; Gibson et al, 2003).