For this purpose, the presence of COX-2 and PPARγ was immunohistochemically examined in 71 epithelial ovarian carcinomas, 18 borderline tumours and 23 benign tumours and the levels of COX-2 and PPARγ proteins were determined by enzyme immunoassay in four benign tumours, three borderline tumours and 12 carcinomas. This evidence concerns the gene PTGS2 and benign neoplasm.