BRINP1 and lip and oral cavity carcinoma: The presence of DBCCR1 hypermethylation in oral tumour-adjacent epithelium is of great interest and should be further investigated in order to elucidate whether local recurrence or field cancerisation in oral cancer patients can be explained, at least in some cases, by the existence of a DBCCR1-hypermethylated field in histologically normal epithelium.