BRINP1 and neoplasm: Notably, three cases showed LOH at 9-11407 located ∼300 kb upstream of DBCCR1, but retention of D9S195 located in intron 1 of DBCCR1. In one case, in which DNA was isolated from both well- and poor-differentiated tumour cells from the same tumour, LOH at D9S195 was found in both populations, but only the poor-differentiated tumour cells showed LOH at 9-11407 and D9S1872 (Figure 1).