ERBB2 and non-small cell lung carcinoma: In a study of serum HER-2 ECD level in NSCLC (Ardizzoni et al, 2001), 20% (16 out of 82) of the patients presented with a high serum level and showed a shorter overall survival when compared with patients having a serum level < 73 fm ml−1 (13.5 ng ml−1).