HOPX and neoplasm: Interestingly, in a series of recent independent reports, this protein under different names (mOB1/HOP/LAGY/NECC1/SMAP31) has been shown to be involved in development (Adu et al, 2002; Chen et al, 2002; Shin et al, 2002; Asanoma et al, 2003; Chen et al, 2003) and has been shown to be a potent tumour suppressor (Asanoma et al, 2003).