TG and thyroid gland carcinoma: Using a ‘high sensitivity’ (40 cycles of PCR), however, resulted in the detection of Tg-mRNA in peripheral blood of 11 out of 13 patients with thyroid cancer and known metastases, 111 out of 137 patients with a history of thyroid cancer without known metastases and also in 61 out of 85 patients with benign thyroid disorders and 41 out of 50 control subjects.