ERBB2 and neoplasm: Similarly, when formalin-fixed tumour tissue blocks from 20 independent surgical specimens (i.e., 10 OSPC vs 10 USPC) were tested for HER-2/neu expression, a moderate to heavy staining was found in 70% of USPC (i.e., 70% score 2+ and 3+, 30% score 1+) vs 10% of OSPC (i.e., 10% score 2+ and 90% score 0 to 1+) (P=0.0002 USPC vs OSPC by student's t-test).