Increased NFκB activity has been observed in CRC (Hardwick et al, 2001) and relative resistance to apoptosis has been attributed to high constitutive NFκB activity in other cancers (Bours et al, 1994; Lind et al, 2001; Charalambous et al, 2003). The gene discussed is NFKB1; the disease is colorectal carcinoma.