We studied the levels of CIC (IgG, IgM and IgA) in 58 diabeticchildren (mean age 12.28±4.04 years, diabetes duration 5.3±3.7 years), 29 ofthem had vascular complications (group 1) and the other 29 were withoutvascular complications (group 2). This evidence concerns the gene CD40LG and diabetes mellitus.