Neurohypophysial receptors belongto the G protein-linked seven-transmembrane receptor superfamily and are encodedby four distinct genes, OTR, V1R, V2Rand V3R. The objective of this study was toidentify the nature of neurohypophysial receptor in thymic T cell subsets purified byimmunomagnetic selection, as well as in murine thymic lymphoma cell lines RL12-NPand BW5147. The gene discussed is OXTR; the disease is thymus lymphoma.