For instance, overexpression of RhoC was found in metastatic lesions of inflammatory breast cancer and pancreatic ductal adenocarcinoma (Suwa et al, 1998; Fritz et al, 2002; Kleer et al, 2002), and upregulation was associated with tumour progression in ovarian carcinoma (Horiuchi et al, 2003). This evidence concerns the gene RHOC and inflammatory breast carcinoma.