So far, human IFN-γ-transduced NB cells have been characterised in vitro for phenotypic features (Coze et al, 1995; Ucar et al, 1995) and ability to stimulate alloreactive T-cell responses in mixed lymphocyte/tumour cell cultures (Coze et al, 1995; Coll et al, 1997). This evidence concerns the gene IFNG and neoplasm.