TYMP and neoplasm: In fact, in a variety of tumour tissues, overexpression of TP was found to correlate significantly with an increase in neovascularisation (Toi et al, 1995; Tanigawa et al, 1996; Matsuura et al, 1999) and poor prognosis (Maeda et al, 1996; Takebayashi et al, 1996; Koukourakis et al, 1998; Toi et al, 1999).