For instance, gene amplification or overexpression of c-Myc protein has also been shown to associate with a better tumour differentiation or a better patient survival for cancer of the testis, ovary, bile ducts, colon and breast (Sikora et al, 1985, 1987; Watson et al, 1986; Polacarz et al, 1989; Voravud et al, 1989; Williams et al, 1990; Melhem et al, 1992; Pietilainen et al, 1995; Diebold et al, 1996; Smith and Goh, 1996; Augenlich et al, 1997; Bieche et al, 1999). Here, MYC is linked to neoplasm.