TP53 and neoplasm: The few studies that compared both immunohistochemical staining and p53 mutation found appreciable staining in tumours harbouring mutations, as expected (Esrig et al, 1993; Cordon-Cardo et al, 1994; Oyasu et al, 1995; Vet et al, 1995; Abdel-Fattah et al, 1998; Bernardini et al, 1999).