After excluding the 28 necropsy-derived BC liver metastases, results were comparable (data not shown), with P-values of <0.0001 (glandular differentiation), 0.02 (central fibrin), 0.08 (fibrin at the interface), <0.0001 (central CA9), 0.009 (CA9 at the interface), 0.0004 (global CA9 score) and 0.001 (macrophage count). The gene discussed is CA9; the disease is breast cancer.