TEK and neoplasm: More recently, markers of activated endothelial cells, such as CD105 (Seon et al, 1997; Kumar et al, 1999; Fonsatti et al, 2001), Tie-2/Tek (Brown et al, 1995; Mustonen and Alitalo, 1995; Takahashi et al, 1995; Yokoyama et al, 2000) and VEGF (Salven et al, 1996; Peters et al, 1998) receptors as prognostic indicators more suitable for identifying stromal vessels resulting from tumour neoangiogenesis, have been reported.